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Influenza A virus structure. The influenzavirus virion is pleomorphic; the viral envelope can occur in spherical and filamentous forms. In general, the virus's morphology is ellipsoidal with particles 100–120 nm in diameter, or filamentous with particles 80–100 nm in diameter and up to 20 μm long. [5]
Cat flu is the common name for a feline upper respiratory disease, which can be caused by one or more possible pathogens: Feline herpes virus, causing feline viral rhinotracheitis (cat common cold; this is the disease most associated with the "cat flu" misnomer), Feline calicivirus, Bordetella bronchiseptica (cat kennel cough), or
Cats with avian influenza exhibit symptoms that can result in death. The avian influenza viruses cats may get include H5N1 or H7N2, [ 1 ] notable pathogenic subtypes of the virus. In order to get the virus, a cat would need to be in contact with infected waterfowl, poultry, or uncooked poultry. [ 2 ]
Feline viral rhinotracheitis (FVR) is an upper respiratory or pulmonary infection of cats caused by Feline herpesvirus, also called Feline herpesvirus 1 (FeHV-1), of the family Herpesviridae. It is also commonly referred to as feline influenza , feline coryza , and feline pneumonia but, as these terms describe other very distinct collections of ...
Cap snatching is best described in influenza viruses, especially influenza A. In Orthomyxoviridae , the viral family of influenza, the RdRp is divided into three subunits: PA, PB1 and PB2. PB1 first binds the 5’ end of the viral RNA (vRNA), activating PB2 and causing the 3’ end of the vRNA to form a double-stranded zone with the 5’ end.
3D model of the flu virion. (M2 labeled in white.) The Matrix-2 (M2) protein is a proton-selective viroporin, integral in the viral envelope of the influenza A virus. The channel itself is a homotetramer (consists of four identical M2 units), where the units are helices stabilized by two disulfide bonds, and is activated by low pH.
Influenza viruses: You’re likely familiar with the seasonal flu, but in the last century there have also been four influenza pandemics: the infamous Spanish Flu pandemic in 1918, the H2N2 flu ...
The subtypes of influenza A virus are estimated to have diverged 2,000 years ago. Influenza viruses A and B are estimated to have diverged from a single ancestor around 4,000 years ago, while the ancestor of influenza viruses A and B and the ancestor of influenza virus C are estimated to have diverged from a common ancestor around 8,000 years ago.