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This is a list of investigational social anxiety disorder drugs, or drugs that are currently under development for clinical use in the treatment of social anxiety disorder (SAD; or social phobia) but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
Vortioxetine was under development for the treatment of generalized anxiety disorder [59] and attention-deficit hyperactivity disorder (ADHD) [60] but development for these indications was discontinued. [61] As of August 2021, vortioxetine remains in development for the treatment of anxiety disorders, binge-eating disorder, and bipolar disorder ...
MDMA (Midomafetamine, 3,4-methylenedioxymethamphetamine, "ecstasy") – serotonin–norepinephrine–dopamine releasing agent and 5-HT 1 and 5-HT 2 receptor agonist – specifically under development as an aid to psychotherapy for post-traumatic stress disorder [14] [15] [16]
Vorapaxar is an antiplatelet drug of the PAR-1 antagonist family. It functions by inhibiting thrombin-related platelet aggregation.This mechanism works by a different pathway from other antiplatelet medications, such as aspirin and P2Y12 inhibitors.
Antiplatelet medications are one of the primary recommendations for treatment of both stable [4] and unstable [5] ischemic heart disease. Most commonly, aspirin is used as a single medication in cases of uncomplicated stable angina , and in some cases of unstable angina .
Sarpogrelate (former developmental code names MCI-9042, LS-187,118) is a drug which acts as an antagonist at the serotonin 5-HT 2A [1] [2] 5-HT 2B, and 5-HT 2C receptors. [3] [4] However, its affinities for the human 5-HT 2C and 5-HT 2B receptors are about one and two orders of magnitude lower than for the human 5-HT 2A receptor, respectively. [3]
[1] [2] Antithrombotics can be used therapeutically for prevention (primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases. [citation ...
Available antiplatelet drugs have delayed onset and offset of action. [10] Since cangrelor's effects are immediate and quickly reversed, it is a more desirable drug for elective treatment of stenotic coronary arteries, high risk acute coronary syndromes treated with immediate coronary stenting, and for bridging those surgery patients who ...
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