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Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. [5] This includes aspergillosis , candidiasis , coccidioidomycosis , histoplasmosis , penicilliosis , and infections by Scedosporium or Fusarium . [ 5 ]
Aspergillus felis is a heterothallic species of fungus in the genus Aspergillus which can cause aspergillosis in humans, dogs and cats. It was described for the first time in 2013 after being isolated from different hosts worldwide (North and South America, Europe, Africa, Northeast Asia, and Asia-Pacific). [1] [2] [3] [4]
Laboratory analysis is the only way to distinguish bird flu from aspergillosis. [citation needed] In dogs, aspergillosis is an uncommon disease typically affecting only the nasal passages (nasal aspergillosis). This is much more common in dolicocephalic breeds. It can also spread to the rest of the body; this is termed disseminated ...
Chronic pulmonary aspergillosis is a long-term fungal infection caused by members of the genus Aspergillus—most commonly Aspergillus fumigatus. [8] The term describes several disease presentations with considerable overlap, ranging from an aspergilloma [12] —a clump of Aspergillus mold in the lungs—through to a subacute, invasive form known as chronic necrotizing pulmonary aspergillosis ...
Some types such as blastomycosis, cryptococcus, coccidioidomycosis and histoplasmosis, affect people who live in or visit certain parts of the world. [18] Others such as aspergillosis , pneumocystis pneumonia , candidiasis , mucormycosis and talaromycosis , tend to affect people who are unable to fight infection themselves. [ 18 ]
Allergic bronchopulmonary aspergillosis (ABPA) is a condition characterised by an exaggerated response of the immune system (a hypersensitivity response) to the fungus Aspergillus (most commonly Aspergillus fumigatus). It occurs most often in people with asthma or cystic fibrosis. [1]
Itraconazole is a relatively well-tolerated drug (although not as well tolerated as fluconazole or voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals: [22] elevated alanine aminotransferase levels are found in 4% of people taking itraconazole
It also has decreased in vitro susceptibilities to multiple antifungals, including amphotericin B, itraconazole, voriconazole, and caspofungin. Aspergillus lentulus is an opportunistic human pathogen that causes invasive aspergillosis with high mortality rates. It has been isolated from clinical and environmental sources.
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