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Interleukin 3 is an interleukin, a type of biological signal that can improve the body's natural response to disease as part of the immune system. [10] In conjunction with other β common chain cytokines GM-CSF and IL-5, IL-3 works to regulate the inflammatory response in order to clear pathogens by changing the abundance of various cell populations via binding at the interleukin-3 receptor.
Interleukin 3 (IL3) is a cytokine that regulates hematopoiesis by controlling the production, differentiation and function of granulocytes and macrophages. [ 15 ] [ 16 ] The protein, which exists in vivo as a monomer, is produced in activated T cells and mast cells, [ 15 ] [ 16 ] and is activated by the cleavage of an N-terminal signal sequence.
The interleukin-3 receptor is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes .
The term interleukin was initially used by researchers for those cytokines whose presumed targets are principally white blood cells (leukocytes). It is now used largely for designation of newer cytokine molecules and bears little relation to their presumed function. The vast majority of these are produced by T-helper cells.
They include interleukin-1 (IL-1), IL-6, IL-12, and IL-18, tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ), and granulocyte-macrophage colony stimulating factor (GM-CSF) and play an important role in mediating the innate immune response. Inflammatory cytokines are predominantly produced by and involved in the upregulation of ...
Towana Looney, 53, is recovering after undergoing kidney surgery — using the organ from a genetically manipulated pig — on Nov. 25 at NYU Langone Health in New York City
2625 14462 Ensembl ENSG00000107485 ENSMUSG00000015619 UniProt P23771 P23772 RefSeq (mRNA) NM_001002295 NM_002051 NM_008091 NM_001355110 NM_001355111 NM_001355112 RefSeq (protein) NP_001002295 NP_002042 NP_032117 NP_001342039 NP_001342040 NP_001342041 Location (UCSC) Chr 10: 8.05 – 8.08 Mb Chr 2: 9.86 – 9.89 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse GATA3 is a transcription ...
We finally—finally—made it to the end of the year. And though the music releases have gone from summer’s deluge to a steady trickle, that doesn’t mean there aren’t some great new songs ...
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related to: interleukin 3 meaning