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Catalase is a tetramer of four polypeptide chains, each over 500 amino acids long. [7] It contains four iron-containing heme groups that allow the enzyme to react with hydrogen peroxide. The optimum pH for human catalase is approximately 7, [8] and has a fairly broad maximum: the rate of reaction does not change appreciably between pH 6.8 and 7 ...
Acatalasia is often the result of mutations in both copies of the CAT gene which codes for the enzyme catalase. [5] There are multiple types of mutation that can cause this condition. Inheriting a single CAT mutation results in hypocatalasia, in which catalase levels are reduced, but still at functional levels. [6]
Cats with the homozygous genotype (MM) die before birth, and stillborn kittens show gross abnormalities of the central nervous system. [3] Cats with the heterozygous genotype (Mm) show severely shortened tail length, ranging from taillessness to a partial, stumpy tail. [3] Some Manx cats die before 12 months old and exhibit skeletal and organ ...
Cat genetics describes the study of inheritance as it occurs in domestic cats. In feline husbandry it can predict established traits ( phenotypes ) of the offspring of particular crosses. In medical genetics , cat models are occasionally used to discover the function of homologous human disease genes.
Pasteurella multocida is a Gram-negative, nonmotile, penicillin-sensitive coccobacillus of the family Pasteurellaceae. [1] Strains of the species are currently classified into five serogroups (A, B, D, E, F) based on capsular composition and 16 somatic serovars (1–16).
Staphylococcus pseudintermedius is a gram-positive spherically shaped bacterium of the genus Staphylococcus [1] found worldwide. [2] It is primarily a pathogen for domestic animals, [3] [4] but has been known to affect humans as well. [5]
Many Pasteurella species are zoonotic pathogens, and humans can acquire an infection from domestic animal bites. [4] [5] In cattle, sheep, and birds, Pasteurella species can cause a life-threatening pneumonia; in cats and dogs, however, Pasteurella is not a cause of disease, and constitutes part of the normal flora of the nose and mouth. [6]
C. upsaliensis is found worldwide, and is a common cause of campylobacteriosis in humans, as well as gastroenteritis in dogs and cats. [3] Human infections are primarily associated with raw or undercooked meat and contaminated water sources, however there is some zoonotic risk associated with the spread from dogs and cats. [4]