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Cardiac diastole is the period of the cardiac cycle when, after contraction, the heart relaxes and expands while refilling with blood returning from the circulatory system. [1] [2] Both atrioventricular (AV) valves open to facilitate the 'unpressurized' flow of blood directly through the atria into both ventricles, where it is collected for the ...
Tetralogy of Fallot is the most common congenital heart disease arising in 1–3 cases per 1,000 births. The cause of this defect is a ventricular septal defect (VSD) and an overriding aorta. These two defects combined causes deoxygenated blood to bypass the lungs and going right back into the circulatory system.
One of the simplest methods of assessing the heart's condition is to listen to it using a stethoscope. [1] In a healthy heart, there are only two audible heart sounds, called S1 and S2. The first heart sound S1, is the sound created by the closing of the atrioventricular valves during ventricular contraction and is normally described as "lub".
The circulatory system is further divided into two major circuits – a pulmonary circulation, and a systemic circulation. [8] [1] [3] The pulmonary circulation is a circuit loop from the right heart taking deoxygenated blood to the lungs where it is oxygenated and returned to the left heart.
Oxygenated blood leaves the lungs through pulmonary veins, which return it to the left part of the heart, completing the pulmonary cycle. [3] [6] This blood then enters the left atrium, which pumps it through the mitral valve into the left ventricle. [3] [6] From the left ventricle, the blood passes through the aortic valve to the aorta.
Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology. [1]
Cardiac excitation-contraction coupling (Cardiac EC coupling) describes the series of events, from the production of an electrical impulse (action potential) to the contraction of muscles in the heart. [1] This process is of vital importance as it allows for the heart to beat in a controlled manner, without the need for conscious input.
The heart is a muscular organ found in humans and other animals. This organ pumps blood through the blood vessels. [1] Heart and blood vessels together make the circulatory system. [2] The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. [3]
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