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Thiazolidinediones may cause slight weight gain but decrease "pathologic" abdominal fat (visceral fat), and therefore may be prescribed for diabetics with central obesity. [115] Thiazolidinedione has been associated with heart failure and increased cardiovascular risk; so it has been withdrawn from the market in Europe by EMA in 2010. [116]
Humulin was the first medication produced using modern genetic engineering techniques in which actual human DNA is inserted into a host cell (E. coli in this case). The host cells are then allowed to grow and reproduce normally, and due to the inserted human DNA, they produce a synthetic version of human insulin.
Even if short sleep does increase weight gain, it is unclear if this is to a meaningful degree or if increasing sleep would be of benefit. [170] Some have proposed that chemical compounds called "obesogens" may play a role in obesity. Certain aspects of personality are associated with being obese. [171]
“There are many medications that may cause weight gain,” says W. Scott Butsch, M.D., director of obesity medicine in the Bariatric and Metabolic Institute at the Cleveland Clinic.
Ongoing stress can lead to cortisol belly fat, as high cortisol levels can promote weight gain around the abdomen. This is due to how the hormone affects fat storage. Disrupted sleep.
The not-so-glamorous term may make you think of annoying weight gain that does not seem to go away no matter what you do (hello, weight-loss plateau) or constantly feeling and looking bloated.
Lack of sufficient sleep has been suggested as a cause for weight gain or the difficulty in maintaining a healthy weight. [10] Two hormones responsible for regulating hunger and metabolism are leptin, which inhibits appetite and increases energy expenditure, and ghrelin, which increases appetite and reduces energy expenditure. [10]
This weight gain can be driven by physical inactivity, stress, poor sleep and poor food choices, such as eating too many ultraprocessed foods, as well as medications, experts say. Weight gain by ...