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There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
In genetics, a locus (pl.: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. [1] Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at ...
Physical map is a technique used in molecular biology to find the order and physical distance between DNA base pairs by DNA markers. [1] It is one of the gene mapping techniques which can determine the sequence of DNA base pairs with high accuracy. Genetic mapping, another approach of gene mapping, can provide markers needed for the physical ...
Where d is the distance in map units, the Morgan Mapping Function states that the recombination frequency r can be expressed as =.This assumes that one crossover occurs, at most, in an interval between two loci, and that the probability of the occurrence of this crossover is proportional to the map length of the interval.
In genetics, a morbid map is a chart or diagram of diseases and the chromosomal location of genes the diseases are associated with. A morbid map exists as an appendix of the Online Mendelian Inheritance in Man (OMIM) knowledgebase, listing chromosomes and the genes mapped to specific sites on those chromosomes, and this format most clearly reveals the relationship between gene and phenotype.
Myc box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene. [5] [6] [7]This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor.
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8590 18317 Ensembl ENSG00000184933 ENSMUSG00000070417 UniProt O95222 n/a RefSeq (mRNA) NM_003696 NM_010983 RefSeq (protein) NP_003687 n/a Location (UCSC) Chr 11: 6.79 – 6.8 Mb Chr 7: 106.59 – 106.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene. It is Class II (tetrapod -specific) olfactory receptor ...