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South Carolina Highway 51 Connector (SC 51 Conn.) is a 0.240-mile (0.386 km) connector route that serves to connect SC 51 and US 52. Its entire length is known as Pamplico Highway and is unsigned . It begins at an intersection with the SC 51 mainline (known as West 2nd Loop Road west of here and also known as Pamplico Highway east of here).
South Carolina Highway 41 (SC 41) is a 121.5-mile (195.5 km) state highway, connecting the Charleston region with eastern portions of the Pee Dee region in South Carolina. It serves as an alternative route to U.S. Route 52 .
U.S. Route 378 (US 378) is a spur of US 78 in the U.S. states of Georgia and South Carolina.The U.S. Highway runs 234.30 miles (377.07 km) from US 78, Georgia State Route 10 (SR 10), SR 17, and SR 47 in Washington, Georgia, east to US 501 Business in Conway, South Carolina.
US 52 crosses the North Carolina state line, after traveling 159.7 miles (257.0 km) through South Carolina, continuing on towards Wadesboro. [ 7 ] US 52 is a major highway between Charleston and Florence, all of which is four-lane or more with some sections signed 60-mile-per-hour (97 km/h).
U.S. Route 176 (US 176) is a spur of US 76 in the U.S. states of North Carolina and South Carolina.The U.S. Highway runs 237.98 miles (382.99 km) from US 25 Business and North Carolina Highway 225 (NC 225) in Hendersonville, North Carolina, east to US 52 in Goose Creek, South Carolina.
South Carolina Highway 527 (SC 527) is a 65.940-mile (106.120 km) state highway in the U.S. state of South Carolina. It travels between Andrews on the Williamsburg–Georgetown county line to Lee County six miles (9.7 km) south of Bishopville. The highway travels in a southeast–northwest direction.
The South Carolina State Highway System is the fourth largest state-maintained system of state highways in the country. It consists of Interstates , U.S. highways , state highways, and secondary roads, totaling approximately 41,500 miles (66,800 km).
US 301 at the SC 260 intersection in Manning.. US 301 was established in 1932 as a replacement of the piece of US 17-1 north of Wilson and the whole of US 217. Thus US 301 initially ran from US 17 (now US 76) at Pee Dee northeast through Dillon, South Carolina, into North Carolina, and Virginia, ending at U.S. Route 1 in Petersburg, Virginia.