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[1] [2] [3] Cohn describes its use to detect the principal components of digitalis (note that they may not be alkaloids). [4] The reaction with this reagent is also known as the Keller–Kiliani reaction, after C. C. Keller and H. Kiliani, who both used it to study digitalis in the late 19th century.
Keller's reagent can refer to two different reagents: Keller's reagent (metallurgy), used to etch aluminum alloys; Keller's reagent (organic), used to detect alkaloids
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. [1] Their beneficial medical uses include treatments for congestive heart failure and cardiac arrhythmias ; however, their relative toxicity prevents them ...
For example, taking normal QTc ≤ 0.42 s, QT would be expected to be 0.42 s or less at a heart rate of 60 bpm. For a heart rate of 70 bpm, QT would roughly be expected to be equal to or below 0.40 s. Likewise, for 80 bpm, QT would roughly be expected to be equal to or below 0.38 s. [13]
The study, which was published in Nature Medicine on January 20, analyzed data from more than 2 million people with diabetes who took GLP-1 receptor agonist medications like Ozempic and Wegovy.
[1] Three methods are used for detecting oleandrin in the blood. Fluorescence polarization immunoassay is widely used. This test is slower and has a lower sensitivity than digoxin immunoassay (Digoxin III). [11] A direct analytic technique like liquid chromatography-electrospray tandem mass spectrometry is used when there are medical or legal ...
A new study compares the benefits and risks of taking GLP-1 medications for weight loss, including risks of dementia, addiction, heart disease, and ... from more than 2 million people taking ...
A radio adaptation of the play by Kate Clanchy was premiered by BBC Radio 3 on 19 June 2011 as part of its Money Talks season and repeated on 1 July 2012. [4] [5] It was the first radio play to be directed by Samuel West (who also played the minor and uncredited vocal role of a French tailor).