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Urolithin A is not known to be found in any food but rather forms as the result of transformation of ellagic acids and ellagitannins by the gut microflora in humans. [ citation needed ] Sources of ellagitannins are: pomegranates, nuts, some berries (raspberries, strawberries, blackberries, cloudberries), tea, muscadine grapes, many tropical ...
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
Hypervitaminosis A refers to the toxic effects of ingesting too much preformed vitamin A (retinyl esters, retinol, and retinal). Symptoms arise as a result of altered bone metabolism and altered metabolism of other fat-soluble vitamins. Hypervitaminosis A is believed to have occurred in early humans, and the problem has persisted throughout ...
[15] [4] [10] [12] [7] It is also possible that some individuals are more susceptible to the toxic effects of vitamin B 6 than others. [4] Megavitamin-B 6 syndrome has been reported in doses as low as 24 mg/day. [34] Symptoms may also be dependent on the form of vitamin B 6 taken in supplements.
Toxicity occurs through overdosage with an appropriate product or use of an agricultural product. Signs for both include hypersalivation, vomiting, lethargy, tremors, difficulty walking, weakness, and death. [174] Chocolate is a common cause of poisoning in dogs. The toxic principles in chocolate are theobromine and caffeine.
Chemical structure of urolithin A.. Urolithins are microflora metabolites of dietary ellagic acid derivatives, such as ellagitannins. [1] They are produced in the gut, and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing foods, such as pomegranate. [2]
Glucocorticoids lower the serum concentration of thyroxine and triiodothyronine. 40-50% of dogs with Cushing's have lowered levels of these thyroid hormones. The cause of this is not known. When a dog has lowered serum levels of thyroid hormones and endocrine alopecia it is harder to differentiate between hypothyroidism and Cushing's.
Although a small preliminary study [54] indicated xylitol may be safe for dogs, other studies show significant toxicity. [55] There have been cases of foods, candies and gums containing xylitol causing toxic or even fatal liver damage in dogs. [56] [57] [58] Ingestion may cause hypoglycemia. [38]