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Tityus stigmurus is a species of scorpion from the family Buthidae that can be found in Brazil. The species are 4.5–6 centimetres (1.8–2.4 in) in length and are either golden-tan or yellowish-brown coloured. It takes them a year to mature into an adult, which makes them a fast-growing species.
Tityus stigmurus toxin 1 (Tst1) is a neurotoxin found in the venom of the Brazilian scorpion, Tityus stigmurus. It acts on voltage-gated sodium channels (Navs), altering opening and inactivation voltages, recovery from inactivation, and overall current flow.
Tityus is a large genus of thick-tailed scorpions (family Buthidae), the namesake of its subfamily Tityinae. As of 2021, Tityus contains more than 220 described species distributed in Central America and South America , from Costa Rica to Argentina .
The venom of Tityus serrulatus is the most potent of the toxins from the species. [3] Tityustoxin-1, TsTX-I is the most toxic protein among the neurotoxins in this venom, with an intravenous and intracisternal LD 50 (mouse) of 76 ± 9 and 1.1 ± 0.3 μg/kg, respectively.
When this sequence was further characterized, it was revealed to be a unique potassium blocker and was named Tst26. Tst was derived from the abbreviation of the species of scorpion it was discovered from, Tityus stigmurus, and 26 was derived from the elution time of the sample it was obtained from. Tst26 has high sequence similarity with other ...
Butantoxin (BuTX) is a compound of the venom of three Brazilian and an Argentinean scorpion species of the genus Tityus. Butantoxin reversibly blocks the voltage-gated K+ channels Shaker B and Kv1.2, and the Ca 2+-activated K + channels K Ca 1.1 and K Ca 3.1.
Tityus serrulatus venom toxins (2 P) Pages in category "Scorpion toxins" The following 73 pages are in this category, out of 73 total. ... Tityus stigmurus toxin 1 ...
Tityus serrulatus; Tityus stigmurus This page was last edited on 26 December 2023, at 18:56 (UTC). Text is available under the Creative Commons Attribution ...