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Brush border cells are found mainly in the following organs: The small intestine tract: This is where absorption takes place. [2] [3] [4] The brush borders of the intestinal lining are the site of terminal carbohydrate digestions. The microvilli that constitute the brush border have enzymes for this final part of digestion anchored into their ...
In prolonged acidosis, PEPCK-C is upregulated in renal proximal tubule brush border cells, in order to secrete more NH 3 and thus to produce more HCO 3 −. [26] The GTP-specific activity of PEPCK is highest when Mn 2+ and Mg 2+ are available. [21] In addition, hyper-reactive cysteine (C307) is involved in the binding of Mn 2+ to the active ...
Thousands of microvilli form a structure called the brush border that is found on the apical surface of some epithelial cells, such as the small intestines. (Microvilli should not be confused with intestinal villi, which are made of many cells. Each of these cells has many microvilli.)
The same experiment also found that upon phosphorylation, a 14-3-3 protein was bound to the phototropins before the H +-ATPase had been phosphorylated. [5] In a similar experiment they concluded that the binding of 14-3-3 protein to the phosphorylation site is essential for the activation of plasma membrane H +-ATPase activity. [6]
Villin-1 is a 92.5 kDa tissue-specific actin-binding protein associated with the actin core bundle of the brush border. [1] Villin-1 is encoded by the VIL1 gene. Villin-1 contains multiple gelsolin -like domains capped by a small (8.5 kDa) "headpiece" at the C-terminus consisting of a fast and independently folding three-helix bundle that is ...
LifeAct peptides have been used as a universal marker for F-actin visualization in biomedical research. An experiment conducted by Sawant et al. utilized LifeAct GFP to visualize the migration of control border cells in the ovaries of Drosophila flies, in order to determine how cells move in terms of small and large collectives during development and cancer. [6]
Plug Power (NASDAQ: PLUG) has been manufacturing these hydrogen fuel cells for years now, and deploying them in forklifts, short-range haulers, robotics, and more recently, longer-range vehicles ...
Their experiment proved the existence of a photosynthetic unit. Gaffron and Wohl later interpreted the experiment and realized that the light absorbed by the photosynthetic unit was transferred. [7] This reaction occurs at the reaction center of Photosystem II and takes place in cyanobacteria, algae and green plants. [8]