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In small ruminants (sheep, goats, deers), swayback is the common term for the enzootic ataxia, a disease in young animals due to copper deficiency in fetal and early postnatal development. See also [ edit ]
Copper deficiency, or hypocupremia, is defined as insufficient copper to meet the body's needs, or as a serum copper level below the normal range. [1] Symptoms may include fatigue, decreased red blood cells, early greying of the hair, and neurological problems presenting as numbness, tingling, muscle weakness, and ataxia. [2]
Copper deficiency is a major issue in global food production, resulting in losses in yield and reduced quality of output. Nitrogen fertilizers can worsen copper deficiency in agricultural soils. [citation needed] The world's two most important food crops, rice and wheat, are highly susceptible to copper deficiency.
manganese deficiency / manganism: Copper: 0.9 10; 5 Required co-factor for cytochrome c oxidase: Liver, seafood, oysters, nuts, seeds; some: whole grains, legumes [29] copper deficiency / copper toxicity: Iodine: 0.150 1.1; 0.6 Required for the synthesis of thyroid hormones and to help enzymes in host defense
Cattle, sheep, goat, and other ruminants that are diagnosed with PEM or pre-PEM suffer opisthotonus, cortical blindness, disoriented movement, and eventually fatality, if left untreated. [1] Current data shows that the onset of PEM can range from birth to late adulthood.
11977 Ensembl ENSG00000165240 ENSMUSG00000033792 UniProt Q04656 Q64430 RefSeq (mRNA) NM_000052 NM_001282224 NM_001109757 NM_009726 RefSeq (protein) NP_000043 NP_001269153 NP_001103227 NP_033856 Location (UCSC) Chr X: 77.91 – 78.05 Mb Chr X: 105.07 – 105.17 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ATP7A, also known as Menkes' protein (MNK), is a copper-transporting P-type ...
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Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.