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Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
Common side effects include headache, sleepiness, change in taste, and sore throat. [8] It is unclear if use is safe during pregnancy or breastfeeding. [9] It is a second-generation antihistamine and works by blocking the release of a number of inflammatory mediators including histamine. [7] [8]
Anti-allergic agents are medications used to treat allergic reactions. Anti-allergic agents have existed since 3000 B.C in countries such as China and Egypt.It was not until 1933 when antihistamines, the first type of anti-allergic agents, were developed. [1]
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. [11] [2] Diphenhydramine is also a potent anticholinergic. [12] It is mainly used to treat allergies, insomnia, and symptoms of the common cold.
Clemastine is an antihistamine with anticholinergic and sedative effects. Antihistamines competitively bind to histamine receptor sites, thus reducing the neurotransmitter's effects. [9] Effects of histamine (which are countered by antihistamines) include: Increased capillary permeability; Increased capillary dilatation; Edema (i.e., swelling ...
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