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  2. Sinoatrial node - Wikipedia

    en.wikipedia.org/wiki/Sinoatrial_node

    The SA node cells are smaller and paler than the surrounding atrial cells, with the average cell being around 8 micrometers in diameter and 20-30 micrometers in length (1 micrometer= 0.000001 meter). [7] Unlike the atrial cells, SA node cells contain fewer mitochondria and myofibers, as well as a smaller sarcoplasmic reticulum.

  3. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    The action potential passes along the cell membrane causing the cell to contract, therefore the activity of the sinoatrial node results in a resting heart rate of roughly 60–100 beats per minute. All cardiac muscle cells are electrically linked to one another, by intercalated discs which allow the action potential to pass from one cell to the ...

  4. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    The cells that make up the SA node are specialized cardiomyocytes known as pacemaker cells that can spontaneously generate cardiac action potentials. These signals are propagated through the heart's electrical conduction system. [1] [2] Only one percent of the heart muscle cells are conductive, the rest of the cardiomyocytes are contractile.

  5. Cardiac conduction system - Wikipedia

    en.wikipedia.org/wiki/Cardiac_conduction_system

    Cells of the ventricles contract nearly simultaneously. The action potentials of cardiac muscle are unusually sustained. This prevents premature relaxation, maintaining initial contraction until the entire myocardium has had time to depolarize and contract. Absence of tetany. After contracting, the heart must relax to fill up again.

  6. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The cardiomyocytes make up the bulk (99%) of cells in the atria and ventricles. These contractile cells respond to impulses of action potential from the pacemaker cells and are responsible for the contractions that pump blood through the body. The pacemaker cells make up just (1% of cells) and form the conduction system of the heart.

  7. Purkinje fibers - Wikipedia

    en.wikipedia.org/wiki/Purkinje_fibers

    Purkinje fibers take up stain differently from the surrounding muscle cells because of having relatively fewer myofibrils than other cardiac cells. The presence of glycogen around the nucleus causes Purkinje fibers to appear, on a slide, lighter and larger than their neighbors, being arranged along the longitudinal direction (parallel to the ...

  8. Heart - Wikipedia

    en.wikipedia.org/wiki/Heart

    The pacemaker cells make up 1% of cells and form the conduction system of the heart. They are generally much smaller than the contractile cells and have few myofibrils which gives them limited contractibility. Their function is similar in many respects to neurons. [8]

  9. Beta-1 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-1_adrenergic_receptor

    153 11554 Ensembl ENSG00000043591 ENSMUSG00000035283 UniProt P08588 P34971 RefSeq (mRNA) NM_000684 NM_007419 RefSeq (protein) NP_000675 NP_031445 Location (UCSC) Chr 10: 114.04 – 114.05 Mb Chr 19: 56.71 – 56.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene ...