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The success of the phase-contrast microscope has led to a number of subsequent phase-imaging methods. In 1952, Georges Nomarski patented what is today known as differential interference contrast (DIC) microscopy. [8] It enhances contrast by creating artificial shadows, as if the object is illuminated from the side.
After its introduction in the 1940s, live-cell imaging rapidly became popular using phase-contrast microscopy. [11] The phase-contrast microscope was popularized through a series of time-lapse movies (see video), recorded using a photographic film camera. [12] Its inventor, Frits Zernike, was awarded the Nobel Prize in 1953. [13]
In science, the concept of a macroscope is the antithesis of the microscope, namely a method, technique or system appropriate to the study of very large objects or very complex processes, for example the Earth and its contents, [1] [2] or conceptually, the Universe. Obviously, a single system or instrument does not presently exist that could ...
This is the basis of the idea of phase contrast imaging. [2] As an example, consider the setup shown in the figure on the right. A schematic illustrating the ray optics of phase contrast imaging. A probe laser is incident on a phase object. This could be an atomic medium such as a Bose-Einstein Condensate. [3]
Antonie van Leeuwenhoek (1632–1723). The field of microscopy (optical microscopy) dates back to at least the 17th-century.Earlier microscopes, single lens magnifying glasses with limited magnification, date at least as far back as the wide spread use of lenses in eyeglasses in the 13th century [2] but more advanced compound microscopes first appeared in Europe around 1620 [3] [4] The ...
By Keith Morrison Taking the phrase of "putting it under the microscope" quite literally, the Nikon Small World contest recently announced its winners for 2014. Now in its 40th year, the contest ...
The non-scanning SHG microscope was used for observation of plant starch, [11] [12] megamolecule, [13] spider silk [14] [15] and so on. In 2010 SHG was extended to whole-animal in vivo imaging. [ 16 ] [ 17 ] In 2019, SHG applications widened when it was applied to the use of selectively imaging agrochemicals directly on leaf surfaces to provide ...
Early world maps cover depictions of the world from the Iron Age to the Age of Discovery and the emergence of modern geography during the early modern period.Old maps provide information about places that were known in past times, as well as the philosophical and cultural basis of the map, which were often much different from modern cartography.