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Splenic sequestration crisis is a life-threatening illness common in pediatric patients with homozygous sickle cell disease and beta thalassemia. Up to 30% of these children may develop splenic sequestration crisis with a mortality rate of up to 15%.
Although symptoms include an enlargement in the size of the spleen, [2] or a change from the spleen's original position to another location, usually in either other parts of the abdomen or into the pelvis. This ability to move to other locations is commonly attributed to the spleen's pedicle being abnormally long. [3]
Cobalt-60 beam machine from 1951 Cobalt units use radiation from cobalt-60, which emits two gamma rays at energies of 1.17 and 1.33 MeV, a dichromatic beam with an average energy of 1.25 MeV. The role of the cobalt unit has largely been replaced by the linear accelerator, which can generate higher energy radiation.
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The Therac-25 is a computer-controlled radiation therapy machine produced by Atomic Energy of Canada Limited (AECL) in 1982 after the Therac-6 and Therac-20 units (the earlier units had been produced in partnership with Compagnie générale de radiologie (CGR) of France).
The spleen is especially prone to damage in SCD due to its role as a blood filter. A splenic sequestration crisis, also known as a spleen crisis, is a medical emergency that occurs when sickled red blood cells block the spleen's filter mechanism, causing the spleen to swell and fill with blood. The accumulation of red blood cells in the spleen ...
The gonads may pick up some tissue from the spleen, and as they descend through the abdomen during development, they can produce either a continuous or a broken line of deposited splenic tissue. [12] Splenosis is a condition where foci of splenic tissue undergo autotransplantation, most often following physical trauma or splenectomy.
High intensity focused ultrasound: Uses a machine that emits high frequency sound waves to kill cancer cells and provide relief for tumor-related pain, such as in the bone. Transarterial embolization (TAE)/ bland embolization : Injection of embolic material (microparticles, alcohol, glue) through a catheter into the arteries feeding a tumor to ...