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Developed by Calvin S. Hall, the open field test is an experimental test used to assay general locomotor activity levels, anxiety, and willingness to explore in animals (usually rodents) in scientific research. However, the extent to which behavior in the open field measures anxiety is controversial.
Elevated plus maze. Schematic drawing of an elevated plus maze. The elevated plus maze ( EPM) is a test measuring anxiety in laboratory animals that usually uses rodents as a screening test for putative anxiolytic or anxiogenic compounds and as a general research tool in neurobiological anxiety research such as PTSD and TBI. [1] The model is ...
The Ames test is a widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism. More formally, it is a biological assay to assess the mutagenic potential of chemical compounds. [1] A positive test indicates that the chemical is mutagenic and therefore may act as a carcinogen ...
Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
University of Michigan faces lawsuit over withholding mouse swim test footage. Gannett. Jennifer Dixon, Detroit Free Press ... Animal Partisan is a legal advocacy organization that aims to end the ...
Knockout mouse. A knockout mouse, or knock-out mouse, is a genetically modified mouse ( Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose ...
The Barnes maze. The Barnes maze is a tool used in psychological laboratory experiments to measure spatial learning and memory. The test was first developed by Dr. Carol Barnes in 1979. [1] The test subjects are usually rodents such as mice or lab rats, which either serve as a control or may have some genetic variable or deficiency present in ...
: 119 Compare to the feature auto-aim. aiming down sights (ADS) Also aim down sights. Refers to the common alternate method of firing a gun in a first-person shooter (FPS) game, typically activated by the right mouse button. The real-life analogue is when a person raises a rifle up and places the stock just inside the shoulder area, and leans ...