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Reactive gastropathy, is characterized histologically by: [2] - Foveolar hyperplasia (black arrow), as a tortuosity in the "neck" region of the gastric glands. - Scant or minimal inflammatory cells (white arrow), i.e. lack of large numbers of neutrophils and plasma cells.. - Smooth muscle hyperplasia in the lamina propria (in black oval).
The usual appearance of portal hypertensive gastropathy on endoscopy is a mosaic-like or reticular pattern in the mucosa. Red spots may or may not be present. The pattern is usually seen throughout the stomach. [2] A similar pattern can be seen with a related condition called gastric antral vascular ectasia (GAVE), or watermelon stomach.
Diagram of the alkaline mucous layer in the stomach with mucosal defense mechanisms. The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety.
Micrograph of Barrett's esophagus (left of image) and normal stratified squamous epithelium (right of image). Alcian blue stain.. Glandular metaplasia is a type of metaplasia where irritated tissue converts to a glandular form.
Foveolar cells or surface mucous cells are mucus-producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid. [1] [a] These cells line the gastric mucosa and the gastric pits. Mucous neck cells are found in the necks of the gastric glands.
The gastric glands open into gastric pits in the mucosa. The gastric mucosa is covered in surface mucous cells that produce the mucus necessary to protect the stomach's epithelial lining from gastric acid secreted by parietal cells in the glands, and from pepsin, a secreted digestive enzyme. Surface mucous cells follow the indentations and ...
The esophageal mucosa (stratified squamous epithelium) is seen on the right. The gastric mucosa (simple columnar epithelium) is seen on the left. The metaplastic epithelial is at the junction (center of image) and has an intensely eosinophilic (bright pink) cytoplasm. H&E stain. Specialty: Oncology
The gastric folds consist of two layers: Mucosal layer – This layer releases stomach acid. It is the innermost layer of the stomach. [5] It is affected by the hormone histamine, which signals it to release hydrochloric acid (HCl). Sub-mucosal layer – This layer consists of different vessels and nerves, ganglion neurons, and adipose tissue ...