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The packaging for valsartan includes a warning stating the drug should not be used with the renin inhibitor aliskiren in people with diabetes. It also states the safety of the drug in severe renal impairment has not been established. [7] Valsartan includes a black box warning for fetal toxicity.
The use of valsartan in pregnancy is avoided due to the potential risk of fetal toxicity. [11] The U.S. Food and Drug Administration has a black box warning for valsartan/hydrochlorothiazide use during pregnancy. [2] The use of hydrochlorothiazide is avoided in those with anuria or severe kidney disease. [12]
Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis , normal growth , differentiation , development or behavior.
The problem, he said, is that “war will break these values. “There is an inherent contradiction between the warrior code, how these guys define themselves, what they expect of themselves – to be heroes, the selfless servants who fight for the rest of us – and the impossibility in war of ever living up to those ideals. It cannot be done.
Fetal warfarin syndrome is a disorder of the embryo which occurs in a child whose mother took the medication warfarin (brand name: Coumadin) during pregnancy. Resulting abnormalities include low birth weight , slower growth , intellectual disability , deafness , small head size , and malformed bones , cartilage , and joints .
An abridged version was released in the United States in 1951 as The Fighting Rats of Tobruk. The film follows three drover friends who enlist in the Australian Army together during World War II. Their story is based on the siege of the Libyan city of Tobruk in North Africa by Rommel's Afrika Korps. The partly Australian defenders held the city ...
This series came from a determination to understand why, and to explore how their way back from war can be smoothed. Moral injury is a relatively new concept that seems to describe what many feel: a sense that their fundamental understanding of right and wrong has been violated, and the grief, numbness or guilt that often ensues.
The following is a list of training films produced for the United States Army and Navy by the Walt Disney Studio during World War II. Most of these films were not sole productions of Disney, but were collaborations with other entities such as the First Motion Picture Unit (FMPU) or Frank Capra's signal corps.