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  2. Acromegaly - Wikipedia

    en.wikipedia.org/wiki/Acromegaly

    Diabetes that occurs with acromegaly is treated with the typical medications, but successful lowering of growth hormone levels often alleviates symptoms of diabetes. [11] Hypogonadism without gonad destruction is reversible with treatment. [11] Acromegaly is associated with a slightly elevated risk of cancer. [30]

  3. Growth hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Growth_hormone_therapy

    GH treatment usually decreases insulin sensitivity, [24] but some studies showed no evidence for increased diabetes incidence in GH-treated adult hypopituitary patients. [ 25 ] In past it was believed that GH treatment could increase the cancer risk; a large study recently concluded that "With relatively short follow-up, the overall primary ...

  4. Gigantism - Wikipedia

    en.wikipedia.org/wiki/Gigantism

    The specific age of onset for gigantism varies between patients and gender, but the common age that excessive growth symptoms start to appear has been found to be around 13 years. [6] Other health complications, such as hypertension , may occur in pediatric patients with hyper-secretion of growth hormone.

  5. Octreotide - Wikipedia

    en.wikipedia.org/wiki/Octreotide

    Octreotide is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), when surgery is contraindicated, pituitary tumors that secrete thyroid-stimulating hormone (thyrotropinoma), [citation needed] diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors ().

  6. Local gigantism - Wikipedia

    en.wikipedia.org/wiki/Local_gigantism

    Local gigantism affecting second toe of a child Local gigantism or localised gigantism is a condition in which a certain part of the body acquires larger than normal size due to excessive growth of the anatomical structures or abnormal accumulation of substances.

  7. Insulin-like growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_1

    A synthetic analog of IGF-1, mecasermin, is used for the treatment of growth failure in children with severe IGF-1 deficiency. [15] Cyclic glycine-proline (cGP) is a metabolite of hormone insulin-like growth factor-1 (IGF-1). It has a cyclic structure, lipophilic nature, and is enzymatically stable which makes it a more favourable candidate for ...

  8. AIDA interactive educational freeware diabetes simulator

    en.wikipedia.org/wiki/AIDA_interactive...

    The AIDA software is intended to serve as an educational support tool and can be used by anyone — person with diabetes, relative of a patient, health care professional (doctor, nurse, clinical diabetes educator, dietician, pharmacist, etc.), or student — even if they may have minimal knowledge of the pathophysiology of diabetes mellitus.

  9. Laron syndrome - Wikipedia

    en.wikipedia.org/wiki/Laron_syndrome

    Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin-C) production in response to growth hormone (GH; hGH; somatotropin). [6]

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