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Wistar rat. The Wistar rat is an outbred albino rat. This breed was developed at the Wistar Institute in 1906 for use in biological and medical research, and is notably the first rat developed to serve as a model organism at a time when laboratories primarily used the house mouse (Mus musculus).
Caspar Wistar (1761–1818), physician and anatomist, grandson of the glassmaker. Isaac J. Wistar (1827-1905), Union general and penologist. Wistar Institute, a biomedical research center in Philadelphia, Pennsylvania, named after the physician. Wistar rat, a strain of albino laboratory rats developed at the institute.
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Twelve school districts in Bucks County recently split the cost of $272,630 to tear down a vacant, century-old research lab where biologists created the world-famous Wistar Rat for the University ...
Spontaneously hypertensive rat (SHR) is a laboratory rat which is an animal model of primary hypertension, used to study cardiovascular disease. It is the most studied model of hypertension measured as number of publications. [ 1 ]
Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over 500 grams (17 + 1 ⁄ 2 oz) in the wild. [2] The term rat is also used in the names of other small mammals that are not true rats. Examples include the North American pack rats (aka wood rats [3]) and a number of species loosely called kangaroo rats. [3]
The Wistar rat, which was the first developed rat model strain. A laboratory mouse or rat strain is a group of animals that is genetically uniform. Strains are used in laboratory experiments. Mouse strains can be inbred, mutated, or genetically modified, while rat strains are usually inbred. A given inbred rodent population is considered ...
The best-known Rattus species are the black rat (R. rattus) and the brown rat (R. norvegicus). The group is generally known as the Old World rats or true rats and originated in Asia. Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over 500 grams (1.1 lb) in the wild.