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Millions of people worldwide have had one shot of two-dose COVID-19 vaccines. Pfizer and Moderna's vaccines are likely 80% effective against symptomatic COVID-19 after one dose.
Pfizer and Moderna vaccines are both safe and have similar effectiveness at preventing COVID-19 illness. ... The CDC does not have preference for one vaccine over the others, and the FDA says they ...
Understanding vaccine doses. One-shot vaccines are really the exception rather than the rule, says John Zaia, MD, director of City of Hope’s Center for Gene Therapy in Duarte, California ...
Number needed to vaccinate (NNV) is a metric used in the evaluation of vaccines, [1] [2] [3] and in the determination of vaccination policy. It is defined as the average number of patients that must be vaccinated to prevent one case of disease. It is a specific application of the number needed to treat metric (NNT).
While the efficacy rates were lower than the Pfizer–BioNTech and Moderna vaccines, its single-dose regimen and normal refrigerator storage requirement (2 to 8 °C) could make it a favorable option for many countries. It has similar efficacy to the Janssen vaccine, another one-shot adenovirus vaccine found to be 66% effective in a global trial.
On December 10, 2020, the FDA granted emergency use to the Pfizer vaccine. On December 14, 2020, the first vaccine doses were administered. Sandra Lindsay of Queens, New York City, was the first American to be administered an FDA-authorized COVID-19 vaccine. The Moderna vaccine was granted emergency use authorization three days later, on ...
For those who’ve previously been vaccinated, only one shot should be necessary to catch up. Those ages 65 and older, or who are severely immunocompromised, however, may need a second dose of the ...
In January 2021, Moderna started development of a new form of its vaccine, called mRNA-1273.351, that could be used as a booster shot against the Beta variant (lineage B.1.351). [ 195 ] [ 186 ] In February 2021, Moderna announced that it had manufactured and shipped sufficient amounts of mRNA-1273.351 to the National Institutes of Health to run ...
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