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Moisture sensitive foods and pharmaceuticals are put in packaging with controlled MVTR to achieve the required quality, safety, and shelf life. In clothing , MVTR as a measure of breathability has contributed to greater comfort for wearers of clothing for outdoor activity.
The SBC grade has over twice the barrier to moisture and oxygen per gram coating weight compared to the historic grades. The most common structures using the super barrier PVDC are triplex configurations 250μ PVC/25μ PE/120gsm PVDC up to 250μ PVC/25μ PE/180gsm PVDC, with WVTR of 0.11 to 0.06 g/m 2 per day and available from various suppliers.
Many dry pharmaceuticals are sensitive to moisture. Tablets may become unstable and the drug may degrade. High barrier packaging (including seals) is necessary but, by itself, is often not enough. Shelf life of a moisture-sensitive drug can be extended by means of desiccants. [11]
COC also has a high moisture barrier for a clear polymer along with a low moisture absorption rate. In medical and analytical applications, COC is noted to be a high purity product with low extractables. COC is also a halogen-free and BPA-free product. Some grades of COC have shown a lack of estrogenic activity. [2]
Colour changing silica may be used to indicate when it should be refreshed. Indication gels typically change from blue to pink (if the indicator is cobalt(II) chloride) as they absorb moisture but other colours may be used. A stopcock may be included to permit the desiccator to be evacuated. Such models are usually known as vacuum desiccators.
When detection of fire accelerants is needed for evidence from a fire investigation, the package must be a vapor barrier. Sometimes a glass jar such as a mason jar is used. Heat sealable nylon plastic bags have also been shown to be effective. [5] [6]
Standard test methods are available for measuring the moisture vapor transmission rate, oxygen transmission rate, etc. of packaging materials. Completed packages, however, involve heat seals, joints, and closures that often reduce the effective barrier of the package.
The BFS process functions similarly to conventional extrusion blow molding, and takes place within a BFS machine. [6] First, a plastic polymer resin is heated to >160 °C and compressed to 35 MPa, [11] [15] allowing it to be extruded in tubular form, [1] and be taken over by an open two-part [16] mold to form the container.
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