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Cressdnaviricota is a phylum of viruses with small, circular single-stranded DNA genomes and encoding rolling circle replication-initiation proteins with the N-terminal HUH endonuclease and C-terminal superfamily 3 helicase domains.
It is unknown whether redondoviruses cause human disease. Some CRESS viruses are known pathogens, such as porcine circovirus type 2 [13] Redondoviruses have been reported associated with periodontitis. In one study, the levels fell with successful treatment. [5]
The prototypic members of the realm are often called CRESS-DNA viruses. CRESS-DNA viruses are associated with a wide range of diseases, including diseases in economically important crops and a variety of diseases in animals. The atypical members of the realm include papillomaviruses and polyomaviruses, which are known to cause various cancers.
Brisavirus has a CRESS DNA genome with 3 open reading frames that are inversely oriented that encode for the capsid and Replication-associated protein protein with a small and larger intergenic region. [4] They replicate using rolling-circle replication like other CRESS viruses. [4]
Smacoviridae is a family of single-stranded DNA viruses. [1] The genomes of this family are small (2.3–2.8 kilobases in length). The name Smacoviridae stands for 'small circular genome virus'. [2] The genomes are circular single-stranded DNA and encode rolling-circle replication initiation proteins (Rep) and unique capsid proteins. As of 2021 ...
Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy.
A 29-year-old man’s debilitating night terrors were the first sign of rare autoimmune disorder that rapidly progressed, landing him in the intensive care unit in a “catatonic state.” Ben ...
Orthopoxvirus particles. A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase.They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong ...