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  2. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    If clumping is seen, the Coombs test is positive; if not, the Coombs test is negative. [ 3 ] Common clinical uses of the Coombs test include the preparation of blood for transfusion in cross-matching , atypical antibodies in the blood plasma of pregnant women as part of antenatal care , and detection of antibodies for the diagnosis of immune ...

  3. Hemolytic disease of the newborn (anti-RhE) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    This test is run from cord blood. [3] In some cases, the direct Coombs will be negative but severe, even fatal HDN can occur. [29] An indirect Coombs needs to be run in cases of anti-C, [30] anti-c, [30] and anti-M. Anti-M also recommends antigen testing to rule out the presence of HDN. [22] Hgb – the infant's hemoglobin should be tested from ...

  4. Hemolytic disease of the newborn (anti-Rhc) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    Blood testing for the mother is called an Indirect Coombs Test (ICT) or an Indirect Agglutination Test (IAT). This test tells whether there are antibodies in the maternal plasma. If positive, the antibody is identified and given a titer. Critical titers are associated with significant risk of fetal anemia and hydrops. [14]

  5. Hemolytic disease of the newborn - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    Positive direct Coombs test (might be negative after fetal interuterine blood transfusion) Blood tests done on the mother. Positive indirect Coombs test; Cell free fetal DNA (cff-DNA) from maternal plasma may be used early in pregnancy to determine whether the fetus expresses the red cell antigen to which the pregnant mother is alloimmunized ...

  6. Hemolytic disease of the newborn (ABO) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    Coombs - after birth, the newborn will have a direct Coombs test run to confirm antibodies attached to the infant's red blood cells. This test is run from cord blood. [5] In some cases, the direct Coombs will be negative but severe, even fatal HDN can occur. [15] An indirect Coombs needs to be run in cases of anti-C, [16] anti-c, [16] or anti-M ...

  7. Hemolytic disease of the newborn (anti-Kell) - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_disease_of_the...

    Coombs - after birth baby will have a direct coombs test run to confirm antibodies attached to the infant's red blood cells. This test is run from cord blood. [2] In some cases, the direct coombs will be negative but severe, even fatal HDN can occur. [35]

  8. Blood compatibility testing - Wikipedia

    en.wikipedia.org/wiki/Blood_compatibility_testing

    Blood compatibility testing is routinely performed before a blood transfusion.The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for incompatibility.

  9. Glucose-6-phosphate dehydrogenase deficiency - Wikipedia

    en.wikipedia.org/wiki/Glucose-6-phosphate_de...

    A "direct antiglobulin test" (Coombs' test) – this should be negative, as hemolysis in G6PD is not immune-mediated; When there are sufficient grounds to suspect G6PD, a direct test for G6PD is the "Beutler fluorescent spot test", which has largely replaced an older test (the Motulsky dye-decolouration test). Other possibilities are direct DNA ...

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