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A gluten-free diet (GFD) is a nutritional plan that strictly excludes gluten, ... Medications and dietary supplements are made using excipients that may contain gluten.
Semaglutide was the top selling medication in the US in 2023, with expenditures of US$38.6 billion. [87] "Ozempic, the semaglutide injection used for T2D treatment, has a list price of $936 in the United States and $169 in Japan.
[41] [42] [33] As occurs in people with coeliac disease, the treatment is a gluten-free diet (GFD) strict and maintained, without making any dietary transgression. [37] Whereas coeliac disease requires adherence to a strict lifelong gluten-free diet, it is not yet known whether NCGS is a permanent, or a transient condition.
In many countries, gluten-free products are available on prescription and may be reimbursed by health insurance plans. Gluten-free products are usually more expensive and harder to find than common gluten-containing foods. [125] Since ready-made products often contain traces of gluten, some coeliacs may find it necessary to cook from scratch. [126]
This condition is known as refractory coeliac disease (RCD), defined as malabsorption due to gluten-related enteropathy (villous atrophy or elevated intraepitheal lymphocytes) after initial or subsequent failure of a strict gluten-free diet (usually 1 year) and after exclusion of any disorder mimicking coeliac disease. [106] [107]
A strict gluten-free diet is the first-line treatment, which should be started as soon as possible. It is effective in most of these disorders. When dementia has progressed to an advanced degree, the diet has no beneficial effect. Cortical myoclonus appears to be treatment-resistant on both gluten-free diet and immunosuppression. [14]
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