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GBL is a prodrug of GHB (naturally produced) and its recreational use comes entirely as a result of this. [33] GBL overdose can cause irrational behavior, severe sickness, coma and death. [34] To bypass GHB restriction laws, home synthesis kits were introduced to transform GBL and/or 1,4-B into GHB.
Some prodrugs, such as γ-butyrolactone (GBL), convert to GHB in the stomach and bloodstream. Other prodrugs exist, such as 1,4-butanediol (1,4-B). [35] GBL and 1,4-B are normally found as pure liquids, but they can be mixed with other more harmful solvents when intended for industrial use (e.g. as paint stripper or varnish thinner). [citation ...
γ-Hydroxyvaleric acid (GHV), also known as 4-methyl-GHB, is a designer drug related to γ-hydroxybutyric acid (GHB). It is sometimes seen on the grey market as a legal alternative to GHB, but with lower potency and higher toxicity, [ 2 ] properties which have tended to limit its recreational use.
1,4-Butanediol, also called Butane-1,4-diol (other names include 1,4-B, BD, BDO and 1,4-BD), [5] is a primary alcohol and an organic compound with the formula HOCH 2 CH 2 CH 2 CH 2 OH. . It is a colorless viscous liquid first synthesized in 1890 via acidic hydrolysis of N,N'-dinitro-1,4-butanediamine by Dutch chemist Pieter Johannes Dekkers, who called it "tetramethylene glyco
GVL behaves as a prodrug to γ-hydroxyvaleric acid (GHV), a drug with similar effects to those of γ-hydroxybutyric acid (GHB), albeit with less potency in comparison. [4] Because GHB is controlled in many parts of the world, while GVL is not, GVL has gained popularity as a legal substitute for GHB.
A man is raising eyebrows online after sharing that he suggested a unique name for his new baby with his wife: the name of his ex-girlfriend. In a post shared on Reddit, the anonymous, 40-year-old ...
GHB/GBL and crystal meth can also increase the risk of injuries due to accidents or sexual encounters that go wrong. These injuries can be as minor as cuts and bruises, but they can also be dangerous in severe cases, such as haemorrhages, anal fissures, ripped anuses, anal prolapse, suffocation, and more.
Black Friday tends to cause a bit of chaos every year. Especially because it’s not so much a single day of good deals as a constantly expanding period of non-stop sales (and annoying ads).