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In the 1920s, Kyusaku Ogino, a Japanese gynecologist, and Hermann Knaus, from Austria, working independently, each made the discovery that ovulation occurs about fourteen days before the next menstrual period. [13] Ogino used his discovery to develop a formula for use in aiding infertile women to time intercourse to achieve pregnancy.
The average age of a girl's first period is 12 to 13 (12.5 years in the United States, [6] 12.72 in Canada, [7] 12.9 in the UK [8]) but, in postmenarchal girls, about 80% of the cycles are anovulatory in the first year after menarche, which declines to 50% in the third year, and to 10% by the sixth. [9]
The latter undergo a period of proliferation and mucification known as cumulus expansion. Mucification is the secretion of a hyaluronic acid-rich cocktail that disperses and gathers the cumulus cell network in a sticky matrix around the ovum. This network stays with the ovum after ovulation and has been shown to be necessary for fertilization.
We really terrify women into thinking that one act of unprotected sex will lead to pregnancy every time." While Gur emphasizes that women can get pregnant from having unprotected sex once, she ...
According to Dr. G. Thomas Ruiz, lead ob-gyn at MemorialCare Orange Coast Medical Center in Fountain Valley, Calif., patients who have not had success in getting pregnant a second time after ...
The WHO defines the perinatal period as "The perinatal period commences at 22 completed weeks (154 days) of gestation and ends seven completed days after birth." [26] Perinatal mortality is the death of fetuses or neonates during the perinatal period. A 2013 study found that "While only a small proportion of births occur before 24 completed ...
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