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Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis , normal growth , differentiation , development or behavior.
An early life stage (ELS) test is a chronic toxicity test using sensitive early life stages like embryos or larvae to predict the effects of toxicants on organisms. [1] ELS tests were developed to be quicker and more cost-efficient than full life-cycle tests, taking on average 1–5 months to complete compared to 6–12 months for a life-cycle test.
Baroda Developmental Screening Test is a screening test for motor-mental assessment of infants, developed from Bayley Scales of Infant Development. [ 1 ] History
It was validated both at the hospital and the community level against the standard Denver Developmental Screening Test. [2]With a sensitivity of 66.7% and specificity of 78.8%, it can be used even by community level health worker for mass screening and takes around 5 minutes to complete. [2]
Category 1 has two subcategories for reproductive and developmental effects. Materials which cause concern for the health of breastfed children have a separate category: effects on or via Lactation. Specific target organ toxicity (STOT) [8] category distinguishes between single and repeated exposure for Target Organ Effects. All significant ...
Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology caused by teratogens.
Lead poisoning interferes with the normal development of a child's brain and nervous system; therefore children are at greater risk of lead neurotoxicity than adults are. [203] In a child's developing brain, lead interferes with synapse formation in the cerebral cortex , neurochemical development (including that of neurotransmitters), and ...
By comparing a child’s development to the developmental age ranges in this tool, it allows providers to identify young children with developmental problems so that they can be referred for help. The tests address four domains of child development : personal-social (for example, waves bye-bye), fine motor and adaptive (puts block in cup ...