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The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
This page was last edited on 27 November 2024, at 03:44 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
[6] [7] Another well characterized set of mutations is the Q151M complex found in multi-drug resistant HIV which decreases reverse transcriptase's efficiency at incorporating NRTIs, but does not affect natural nucleotide incorporation. The complex includes Q151M mutation along with A62V, V75I, F77L, and F116Y.
AIDS Healthcare Foundation (AHF) is a Los Angeles-based 501(c)(3) nonprofit organization that provides HIV/AIDS prevention, treatment, and advocacy services. [4] As of 2024, AHF operates about 400 clinics, 69 outpatient healthcare centers, 62 pharmacies, and 22 Out of the Closet thrift stores across 15 U.S. states, Washington, D.C., Puerto Rico, and 46 countries, with over 5,000 employees, and ...
The FDA approved the drug (via the then-new FDA accelerated approval system) for use against HIV, AIDS, and AIDS Related Complex (ARC, a now-obsolete medical term for pre-AIDS illness) on March 20, 1987. [69] The time between the first demonstration that AZT was active against HIV in the laboratory and its approval was 25 months.
The drug works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. By interfering with this process, which is central to the replication of HIV, emtricitabine can help to lower the amount of HIV, or " viral load ", in a patient's body and can indirectly increase the number of immune system cells (namely T ...
HIV climbs nationally among people who inject drugs, data show People who inject drugs made up 8% of the 32,100 estimated new HIV cases nationally in 2021, the latest year the data is available.
Nevirapine (NVP), sold under the brand name Viramune among others, is a medication used to treat and prevent HIV/AIDS, specifically HIV-1. [5] It is generally recommended for use with other antiretroviral medications. [5] It may be used to prevent mother to child spread during birth but is not recommended following other exposures. [5] It is ...