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  2. Mitogen-activated protein kinase - Wikipedia

    en.wikipedia.org/wiki/Mitogen-activated_protein...

    The first mitogen-activated protein kinase to be discovered was ERK1 in mammals. Since ERK1 and its close relative ERK2 are both involved in growth factor signaling, the family was termed "mitogen-activated". With the discovery of other members, even from distant organisms (e.g. plants), it has become increasingly clear that the name is a ...

  3. Mitogen-activated protein kinase kinase - Wikipedia

    en.wikipedia.org/wiki/Mitogen-activated_protein...

    Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK). MAP2K is classified as EC 2.7.12.2 .

  4. Mitogen - Wikipedia

    en.wikipedia.org/wiki/Mitogen

    Mitogens can be either endogenous or exogenous factors. Endogenous mitogens function to control cell division is a normal and necessary part of the life cycle of multicellular organisms. For example, in zebrafish, an endogenous mitogen Nrg1 is produced in response to indications of heart damage. When it is expressed, it causes the outer layers ...

  5. MAP2K1 - Wikipedia

    en.wikipedia.org/wiki/MAP2K1

    MAP2K1 is also known as MEK1 (see Mitogen-activated protein kinase kinase). MEK1 is a meiotic chromosome-axis-associated kinase that is thought to slow down, but not entirely block, sister chromatid recombination. Loss of MEK1 allows inter-sister DSB repair and also inter-sister Holliday junction intermediates to increase.

  6. MAPK1 - Wikipedia

    en.wikipedia.org/wiki/MAPK1

    Mitogen-activated protein kinase 1 (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. [5] Function.

  7. MAP3K1 - Wikipedia

    en.wikipedia.org/wiki/MAP3K1

    Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) is a signal transduction enzyme that in humans is encoded by the autosomal MAP3K1 gene. [5] [6] Function.

  8. MAP3K7 - Wikipedia

    en.wikipedia.org/wiki/MAP3K7

    Mitogen-activated protein kinase kinase kinase 7 (MAP3K7), also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. [5] Structure.

  9. MAP3K3 - Wikipedia

    en.wikipedia.org/wiki/MAP3K3

    Mitogen-activated protein kinase kinase kinase 3 is an enzyme that in humans is encoded by the MAP3K3 gene, [5] which is located on the long arm of chromosome 17 (17q23.3). [ 6 ] Function