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Erythropoietin (/ ɪ ˌ r ɪ θ r oʊ ˈ p ɔɪ. ɪ t ɪ n,-r ə-,-p ɔɪ ˈ ɛ t ɪ n,-ˈ iː t ɪ n /; [1] [2] [3] EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.
Erythropoietin in neuroprotection is the use of the glycoprotein erythropoietin (Epo) for neuroprotection. Epo controls erythropoiesis , or red blood cell production. Erythropoietin and its receptor were thought to be present in the central nervous system according to experiments with antibodies that were subsequently shown to be nonspecific.
Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a novel class of oral medications developed for the treatment of anemia in chronic kidney disease (CKD). These drugs work by inhibiting hypoxia-inducible factor-proline dioxygenase (HIF prolyl-hydroxylase), which are responsible for the degradation of hypoxia-inducible factor ...
The 2020 Cochrane Anaesthesia Review Group review of erythropoietin (EPO) plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery [11] demonstrated that patients were much less likely to require red cell transfusion and in those transfused, the volumes were unchanged (mean ...
7428 22346 Ensembl ENSG00000134086 ENSMUSG00000033933 UniProt P40337 P40338 RefSeq (mRNA) NM_000551 NM_198156 NM_001354723 NM_009507 RefSeq (protein) NP_000542 NP_937799 NP_001341652 NP_000542.1 NP_033533 Location (UCSC) Chr 3: 10.14 – 10.15 Mb Chr 6: 113.6 – 113.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The Von Hippel–Lindau tumor suppressor also known as pVHL is a ...
Drinking a glass of water before meals can help, too. PeopleImages. 5. Eat More Mindfully.
The Bengals grabbed him with the 80th overall pick, with the clear intention of setting up a potential replacement for Pro Bowl wide receiver Tee Higgins should Higgins leave in free agency.
Belzutifan is the first hypoxia-inducible factor-2 alpha inhibitor therapy approved in the US. [17] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [18] Belzutifan is the first medication to be awarded an "innovation passport" from the UK Medicines and Healthcare products Regulatory Agency. [19] [20]