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  2. Inbreeding - Wikipedia

    en.wikipedia.org/wiki/Inbreeding

    Animals avoid inbreeding only rarely. [2] Inbreeding results in homozygosity which can increase the chances of offspring being affected by recessive traits. [3] In extreme cases, this usually leads to at least temporarily decreased biological fitness of a population [4] [5] (called inbreeding depression), which is its ability to survive and ...

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  4. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    1 in 7,500 males (haemophilia A), 1 in 40,000 males (haemophilia B) [2] [5] Haemophilia ( British English ), or hemophilia ( American English ) [ 6 ] (from Ancient Greek αἷμα ( haîma ) 'blood' and φιλία ( philía ) 'love of'), [ 7 ] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots , a process ...

  5. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    [2] [3] In most species with XY sex determination, an organism must have at least one X chromosome in order to survive. [4] [5] The XY system contrasts in several ways with the ZW sex-determination system found in birds, some insects, many reptiles, and various other animals, in which the heterogametic sex is female.

  6. Obligate carrier - Wikipedia

    en.wikipedia.org/wiki/Obligate_carrier

    In X-linked recessive disorders, only females can be the carriers of the recessive mutation, making them obligate carriers of this type of disease. Females acquire one X-chromosome from their father and one from their mother, and this means they can either be heterozygous for the mutated allele or homozygous. If heterozygous, she is a carrier ...

  7. $2.9 million gene therapy for severe hemophilia is approved ...

    www.aol.com/news/gene-therapy-severe-hemophilia...

    U.S. officials on Thursday approved drugmaker BioMarin's gene therapy for the most common form of hemophilia, a $2.9 million infused treatment that can significantly reduce dangerous bleeding ...

  8. Factor IX - Wikipedia

    en.wikipedia.org/wiki/Factor_IX

    In human, the F9 gene is located on the X chromosome at position q27.1. Because the gene for factor IX is located on the X chromosome (Xq27.1-q27.2), loss-of-function mutations thereof are X-linked recessive: males experience the disease phenotype much more frequently than females

  9. This Cartoonist Unveils What Animals Might Say If They ... - AOL

    www.aol.com/lifestyle/cartoonist-unveils-animals...

    Jimmy Craig's They Can Talk comics humorously imagine what animals might say if they could talk. From cats and dogs to birds and raccoons, Craig brings their inner thoughts to life in a funny and ...