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The Reproducibility Project is a series of crowdsourced collaborations aiming to reproduce published scientific studies, finding high rates of results which could not be replicated. It has resulted in two major initiatives focusing on the fields of psychology [ 1 ] and cancer biology. [ 2 ]
Study replication rates were 23% for the Journal of Personality and Social Psychology, 48% for Journal of Experimental Psychology: Learning, Memory, and Cognition, and 38% for Psychological Science. Studies in the field of cognitive psychology had a higher replication rate (50%) than studies in the field of social psychology (25%). [77]
Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
A 2015 study of 100 psychology papers conducted by Open Science Collaboration has been confronted with the "lack of a single accepted definition" which "opened the door to controversy about their methodological approach and conclusions" and made it necessary to fall back on "subjective assessments" of result reproducibility.
Replication (scientific method), one of the main principles of the scientific method, a.k.a. reproducibility Replication (statistics), the repetition of a test or complete experiment; Replication crisis; Self-replication, the process in which an entity (a cell, virus, program, etc.) makes a copy of itself
Example of direct replication and conceptual replication. There are two main types of replication in statistics. First, there is a type called “exact replication” (also called "direct replication"), which involves repeating the study as closely as possible to the original to see whether the original results can be precisely reproduced. [3]
The mechanism by which this damage occurs is still not known. One possibility is that reduced origin activation leads to incomplete DNA replication. Significant re-replication is only observed when all CDK regulatory pathways are inhibited. [25] In mammalian cells, Cdt1 and Cdc6 are much more important to re-replication regulation. [25]
Eukaryotic DNA replication. Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.