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The miR-15 microRNA precursor family is made up of small non-coding RNA genes that regulate gene expression. The family includes the related mir-15a and mir-15b sequences, as well as miR-16-1, miR-16-2, miR-195 and miR-497. These six highly conserved miRNAs are clustered on three separate chromosomes. [1]
Mir-9/mir-79 microRNA precursor family; Mir-10 microRNA precursor family; Mir-11 microRNA precursor family; Mir-14 microRNA precursor family; Mir-15 microRNA precursor family; Mir-16 microRNA precursor family; Mir-17 microRNA precursor family; Mir-19 microRNA precursor family; Mir-22; Mir-23 microRNA precursor family; Mir-24 microRNA precursor ...
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For example, the pre-miRNAs hsa-mir-194-1 and hsa-mir-194-2 lead to an identical mature miRNA (hsa-miR-194) but are from genes located in different genome regions. Species of origin is designated with a three-letter prefix, e.g., hsa-miR-124 is a human ( Homo sapiens ) miRNA and oar-miR-124 is a sheep ( Ovis aries ) miRNA.
MicroRNA-19, or miR-19, is a member of the OncomiR-1 family, and consists of three sub classifications in both humans and mice: mir-19a, mir-19b1 and miR-19b2. miR-19 has been shown to downregulate phosphatase and tensin homolog (PTEN) effectively increasing activity of the cellular survival-promoting signal pathway PI3K-Akt. [11]
Texas Lt. Gov. Dan Patrick said U.S.-owned border wall materials, which were available for sale, were pulled from an Arizona auction at the government's request. The Lonestar State had shown ...
The miR-16 microRNA precursor family is a group of related small non-coding RNA genes that regulates gene expression. miR-16, miR-15, mir-195 and miR-497 are related microRNA precursor sequences from the mir-15 gene family (). This microRNA family appears to be vertebrate specific and its members have been predicted or experimentally validated ...
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