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Recurrent miscarriage or recurrent pregnancy loss (RPL) is the spontaneous loss of 2-3 pregnancies that is estimated to affect up to 5% of women. The exact number of pregnancy losses and gestational weeks used to define RPL differs among medical societies. [ 1 ]
Approximately 15% of recurrent miscarriages are related to immunologic factors. [95] The presence of anti-thyroid autoantibodies is associated with an increased risk with an odds ratio of 3.73 and 95% confidence interval 1.8–7.6. [96] Having lupus also increases the risk of miscarriage. [97]
Immunisation of mothers against male-specific minor histocompatibility (H-Y) antigens has a pathogenic role in many cases of secondary recurrent miscarriage, that is, recurrent miscarriage in pregnancies succeeding a previous live birth. An example of this effect is that the male:female ratio of children born prior and subsequent to secondary ...
In a comparison of 183 women, the researchers found recurrent miscarriage patients showed several signs of having fewer stem cells in the womb.
[3] [13] [7] [14] [11] Those who experience recurrent miscarriage (>3) have a greater risk of developing PTSD than those who have experienced miscarriage once. [3] An association between the gender of the infant lost through miscarriage exists whereby there is an increased chance of developing PTSD if the infant was a male.
The prevalence of uterine malformation is estimated to be 6.7% in the general population, slightly higher (7.3%) in the infertility population, and significantly higher in a population of women with a history of recurrent miscarriages (16%).
This page was last edited on 18 December 2022, at 15:26 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
A bicornuate uterus is an indication for increased surveillance of a pregnancy, though most women with a bicornuate uterus are able to have healthy pregnancies. [1] Women with a bicornuate uterus are at an increased risk of recurrent miscarriage, [2] [10] preterm birth, [2] [11] malpresentation, [2] [12] disruptions to fetal growth, [13] premature rupture of membranes, placenta previa and ...