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Chlorhexidine [1] is a disinfectant and antiseptic with the molecular formula C 22 H 30 Cl 2 N 10, which is used for skin disinfection before surgery and to disinfect surgical instruments. [2] It is also used for cleaning wounds , preventing dental plaque , treating yeast infections of the mouth , and to keep urinary catheters from blocking. [ 3 ]
Skin disinfection may be accomplished with a number of solutions including providone-iodine, chlorhexidine, alcohol based solutions, and cetrimide. [2] There is strong evidence that chlorhexidine and denatured alcohol use to clean skin prior to surgery is better than any other commercially available antiseptic, such as povidone-iodine with alcohol.
It was first discovered and developed by ICI and introduced under the brand name Cetavlon. [2] It is used as a 1-3 % solution for cleaning roadside accident wounds. [3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to Johnson & Johnson in May 1992. [4]
cationic surfactants, such as 0.05–0.5% benzalkonium, 0.5–4% chlorhexidine, 0.1–2% octenidine solutions. Others are generally not applicable as safe antiseptics, either because of their corrosive or toxic nature.
A 2% solution, stabilized for extended use, achieves high-level disinfection in 5 minutes, and is suitable for disinfecting medical equipment made from hard plastic, such as in endoscopes. [31] The evidence available suggests that products based on Accelerated Hydrogen Peroxide, apart from being good germicides, are safer for humans and benign ...
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Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. [1] [2] It may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for. [2]
On Monday, President Joe Biden signed an executive order that will give most federal employees a 2% increase starting January 2025.
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