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The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid secretion. [ citation needed ] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor ...
The lowest pH of the secreted acid is 0.8, [7] but the acid is diluted in the stomach lumen to a pH of between 1 and 3. There is a small continuous basal secretion of gastric acid between meals of usually less than 10 mEq/hour. [8] There are three phases in the secretion of gastric acid which increase the secretion rate in order to digest a ...
“Staying hydrated helps dilute stomach acid,” says Mohammad A Al-Haddad, ... Though not a condition, taking certain medications may exacerbate acid reflux. Medications such as NSAIDs, certain ...
It suppresses stomach acid secretion by specific inhibition of the H + /K +-ATPase system found at the secretory surface of gastric parietal cells. Because this enzyme system is regarded as the acid (proton, or H +) pump within the gastric mucosa, omeprazole inhibits the final step of acid production. [51]
A new study found a link between certain types of acid reflux medications and dementia. The study analyzed data from more than 5,000 people.
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