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Methenamine, also known as 1,3,5,7-tetraazaadamantane, is a simple cyclic hydrocarbon with a cage-like structure and is similar in structure to adamantane (tricyclo[3.3.1.1 3,7]decane). [2] [13] [7] [8] [37] It is specifically the analogue of adamantane in which the carbon atoms at the 1, 3, 4, and 7 positions have been replaced with nitrogen ...
[4] [5] It may also help dry out secretions resulting from skin irritation. [1] It is applied on the skin as a cream or lotion. [2] Side effects may include skin irritation. [4] It is considered to be safe in pregnancy. [4] Calamine is a combination of zinc oxide and 0.5% ferric oxide (Fe 2 O 3). [6]
Imiquimod is a patient-applied cream prescribed to treat genital warts, Bowens disease (squamous cell carcinoma in situ), and, secondary to surgery, for basal cell carcinoma, [7] [8] as well as actinic keratosis. [9] Imiquimod 5% cream is indicated for the topical treatment of: external genital and perianal warts (condylomata acuminata) in ...
The bitartrate salt of DMAE, i.e. N,N-dimethylethanolamine bitartrate, is sold as a dietary supplement. [5] It is a white powder providing 37% DMAE. [6] Animal tests show possible benefit for improving spatial memory [7] and working memory. [8]
[5] C 10 H 7 OH + CH 3 NCO → C 10 H 7 OC(O)NHCH 3. Alternatively, 1-naphthol can be treated with excess phosgene to produce 1-naphthyl chloroformate, which is then converted to carbaryl by reaction with methylamine. [5] The former process was carried out in Bhopal. In comparison, the latter synthesis uses exactly the same reagents, but in a ...
Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. [5] Specific condition with hyperkeratosis where urea cream is useful include: Dry skin and rough skin [5] Dermatitis [5]
Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active drug in humans.
The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. Hydrolysis of the acyl-N bond occurs in the presence of acids: CH 3 CON(CH 3) 2 + H 2 O + HCl → CH 3 COOH + (CH 3) 2 NH 2 + Cl −. However, it is resistant to bases. For this reason DMA is a useful solvent for reactions involving strong bases such as sodium ...