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Anesthetic machine, showing sevoflurane (yellow) and isoflurane (purple) vaporizers on the right. An anesthetic vaporizer (American English) or anaesthetic vapouriser (British English) is a device generally attached to an anesthetic machine which delivers a given concentration of a volatile anesthetic agent. It works by controlling the ...
General anesthesia does not always require the anesthetic machine, tested daily, as basic equipment. Anesthesia machines may differ in appearance, size and degree of sophistication but generally speaking, they consist of sections for: ventilation; Peripheral Nerve Stimulator; space for monitoring equipment; accessories; storage space; worktop
Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.
Halothane, sold under the brand name Fluothane among others, is a general anaesthetic. [5] It can be used to induce or maintain anaesthesia. [5] One of its benefits is that it does not increase the production of saliva, which can be particularly useful in those who are difficult to intubate. [5]
To determine the depth of anesthesia, the anesthetist relies on a series of physical signs of the patient. In 1847, John Snow (1813–1858) [ 1 ] and Francis Plomley [ 2 ] attempted to describe various stages of general anesthesia, but Guedel in 1937 described a detailed system which was generally accepted.
Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia.Like halothane, enflurane, and isoflurane, it is a racemic mixture of (R) and (S) optical isomers (enantiomers).
General anaesthetics can be administered either as gases or vapours (inhalational anaesthetics), or as injections (intravenous or even intramuscular).All of these agents share the property of being quite hydrophobic (i.e., as liquids, they are not freely miscible—or mixable—in water, and as gases they dissolve in oils better than in water).
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.