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Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
For this reason, some dermatologists have started writing prescriptions for full-dose isotretinoin and instructing their patients to microdose themselves by taking the medication only on certain ...
The name isotretinoin is the same root tretinoin plus the prefix iso-. Regarding pronunciation, the following variants apply equally to both tretinoin and isotretinoin. Given that retinoic is pronounced / ˌ r ɛ t ɪ ˈ n oʊ ɪ k /, [43] [44] [42] [45] it is natural that / ˌ t r ɛ t ɪ ˈ n oʊ ɪ n / is a commonly heard pronunciation.
Isotretinoin is a pharmaceutical derivative of retinoic acid (a metabolite of vitamin A). Its mechanism of action is believed to involve reduction in the amount of sebum produced by sebaceous glands on the skin's surface.
Once a doctor decides a patient is a candidate for isotretinoin, [10] they counsel the patient to ensure they understand the drug and the potential side effects. Once the patient signs the necessary paperwork, their doctor will give them a patient ID number, ID card, and program educational materials.
Bremner's research used PET brain imaging to show a decrease in frontal lobe brain function in acne patients treated with Accutane (isotretinoin). He was an expert witness in litigation related to the relationship between Accutane and suicide and depression, including the case of Charles J. Bishop , [ 3 ] which he describes in the narrative non ...
Acitretin, sold under the brand names Neotigason [2] and Soriatane, [5] is a second-generation retinoid.It is taken orally, and is typically used for psoriasis. [6]Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis.
The Department of Public Works and Highways (Filipino: Kagawaran ng mga Pagawain at Lansangang Bayan), abbreviated as DPWH, is the executive department of the Philippine government solely vested with the mandate to “be the State's engineering and construction arm” and, as such, “tasked to carry out the policy” of the State to “maintain an engineering and construction arm and ...