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The passage of steam drew the medicine into the vapor, and the patient inhaled this vapor through a mouthpiece made of glass. [26] Dr Siegle's steam nebulizer, Thackray Museum of Medicine [27] The first pneumatic nebulizer fed from an electrically driven gas (air) compressor was invented in the 1930s and called a Pneumostat.
Nasal budesonide inhalers have been associated with a number of side effects. [ 34 ] [ 35 ] These include nose irritation or burning, bleeding or sores in the nose, lightheadedness, upset stomach, cough, hoarseness, dry mouth, rash, sore throat, bad taste in mouth , change in mucus , and blurred vision. [ 36 ]
Potentially serious side effects include urinary retention, worsening spasms of the airways, and a severe allergic reaction. [3] It appears to be safe in pregnancy and breastfeeding . [ 3 ] [ 9 ] Ipratropium is a short-acting muscarinic antagonist , [ 10 ] which works by causing smooth muscles to relax.
Pulmonary drug delivery is mainly utilized for topical applications in the lungs, such as the use of inhaled beta-agonists, corticosteroids and anticholinergic agents for the treatment of asthma and COPD, the use of inhaled mucolytics and antibiotics for the treatment of cystic fibrosis (CT) and respiratory viral infections, [1] and the use of inhaled prostacyclin analogs for the treatment of ...
Pentamidine can be given by injection into a vein or muscle or by inhalation. [1] Common side effects of the injectable form include low blood sugar, pain at the site of injection, nausea, vomiting, low blood pressure, and kidney problems. [1] Common side effects of the inhaled form include wheezing, cough, and nausea. [1]
Serious side effects can include malignant hyperthermia or high blood potassium. [4] It should not be used in patients with a history of malignant hyperthermia in either themselves or their family members. [3] It is unknown if its use during pregnancy is safe for the fetus, but use during a cesarean section appears to be safe.
Aspiration can result in patient death through a variety of mechanisms. It is important to recognize and diagnose early in order to improve patient outcomes. Death from aspiration and aspiration-related syndromes is most common in elderly patients with known baseline risk factors, though it frequently goes unrecognized. [18]
Salbutamol is usually used with an inhaler or nebulizer, but it is also available in a pill, liquid, and intravenous solution. [8] [10] Onset of action of the inhaled version is typically within 15 minutes and lasts for two to six hours. [8] Common side effects include shakiness, headache, fast heart rate, dizziness, and feeling anxious. [8]
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