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  2. Dantrolene - Wikipedia

    en.wikipedia.org/wiki/Dantrolene

    Dantrolene sodium, sold under the brand name Dantrium among others, is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. [ 5 ] [ 6 ] [ 7 ] It achieves this by inhibiting Ca 2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors . [ 8 ]

  3. Muscle relaxant - Wikipedia

    en.wikipedia.org/wiki/Muscle_relaxant

    Major adverse effects of dantrolene include general muscle weakness, sedation, and occasionally hepatitis. [ 5 ] Other common spasmolytic agents include: methocarbamol , carisoprodol , chlorzoxazone , cyclobenzaprine , gabapentin , metaxalone , and orphenadrine .

  4. Malignant hyperthermia - Wikipedia

    en.wikipedia.org/wiki/Malignant_hyperthermia

    After weighing its questionable benefits against its possible adverse effects (including nausea, vomiting, muscle weakness and prolonged duration of action of nondepolarizing neuromuscular blocking agents [32]), experts no longer recommend the use of prophylactic dantrolene prior to trigger-free general anesthesia in MH-susceptible patients. [30]

  5. Neuroleptic malignant syndrome - Wikipedia

    en.wikipedia.org/wiki/Neuroleptic_malignant_syndrome

    Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]

  6. Thiocolchicoside - Wikipedia

    en.wikipedia.org/wiki/Thiocolchicoside

    Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.

  7. Suxamethonium chloride - Wikipedia

    en.wikipedia.org/wiki/Suxamethonium_chloride

    Common side effects include low blood pressure, increased saliva production, muscle pain, and rash. [7] Serious side effects include malignant hyperthermia , hyperkalemia and allergic reactions . [ 8 ] [ 9 ] It is not recommended in people who are at risk of high blood potassium or a history of myopathy . [ 6 ]

  8. Red Dye 3 Just Got Banned. These Are the Foods to Avoid If ...

    www.aol.com/red-dye-3-just-got-134800003.html

    The FDA’s recent ban on Red Dye No. 3, set to take effect by 2027 for foods and 2028 for drugs, marks a significant step in addressing safety concerns over artificial food dyes in the U.S. food ...

  9. Neuromuscular-blocking drug - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular-blocking_drug

    Although having many unwanted side-effects, a slow onset of action and recovery rate it was a big success and at the time the most potent neuromuscular drug available. Pancuronium and some other neuromuscular blocking agents block M2-receptors and therefore affect the vagus nerve , leading to hypotension and tachycardia .

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