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Newborn screening programs initially used screening criteria based largely on criteria established by JMG Wilson and F. Jungner in 1968. [6] Although not specifically about newborn population screening programs, their publication, Principles and practice of screening for disease proposed ten criteria that screening programs should meet before being used as a public health measure.
Metascreen, as a newborn metabolic screening test, was first launched by Cordlife in India in October 2013. [1] Since April 2014, Metascreen became available also in Hong Kong and the Philippines through Cordlife for parents looking for more comprehensive screening of metabolic disorders for their children.
The following disorders are additional conditions that may be detected by screening. Many are listed as "secondary targets" by the 2005 ACMG report. [1] Some states are now screening for more than 50 congenital conditions. Many of these are rare and unfamiliar to pediatricians and other primary health care professionals. [1] Blood cell disorders
The blood of a two-week-old infant is collected for a Phenylketonuria, or PKU, screening. The neonatal heel prick is a blood collection procedure done on newborns. It consists of making a pinprick puncture in one heel of the newborn to collect their blood. This technique is used frequently as the main way to collect blood from neonates.
Dra. Padilla is a leading advocate for newborn screening. [4] She and her colleagues helped to establish the Newborn Screening System (NBS) in the Philippines, which began as a data gathering project in Metro Manila in 1996. She is the founding president of the Newborn Screening Society of the Philippines. [5]
A blood sample is collected with a heel prick from the newborn 24–48 hours after birth and sent to the lab for analysis. In the United States, newborn screening procedure varies state by state, but all states by law test for at least 21 disorders. If abnormal results are obtained, it does not necessarily mean the child has the disorder.
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The Expanded Program on Immunization (EPI) in the Philippines began in 1976 [1] through Presidential Decree No. 996 signed by President Ferdinand Marcos. [2] And, in 1986, made a response to the Universal Child Immunization goal. The four major strategies include: [3]