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The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
Cervical squamous intraepithelial lesion (SIL), previously called cervical intraepithelial neoplasia (CIN), is a form of dysplasia that can progress to cervical cancer. The term carcinoma in situ may be used interchangeably with high-grade SIL. [8] Ductal carcinoma in situ of the breast is the most common precancer in women.
Cervical intraepithelial neoplasia (CIN) means the development of abnormal cells on the surface of the cervix. It is caused by an HPV infection but in most cases, it is resolved by the immune system. However, a small percentage of people might develop a more serious CIN which, if left untreated, can develop into cervical cancer.
The Bethesda system (TBS), officially called The Bethesda System for Reporting Cervical Cytology, is a system for reporting cervical or vaginal cytologic diagnoses, [1] used for reporting Pap smear results. It was introduced in 1988 [2] and revised in 1991, [3] 2001, [1] [4] [5] and 2014. [6]
HPV disease is the leading cause of cervical cancer, therefore making the HPV vaccine the primary prevention measure for the cancer. Screening with the Papanicolaou (Pap) test is consequently the second measure of prevention. [27] The test identifies cells that are precancerous, and are often credited for the reduced mortality. [28]
The basic unit of length in the imperial and U.S. customary systems is the yard, defined as exactly 0.9144 m by international treaty in 1959. [2] [10] Common imperial units and U.S. customary units of length include: [11] thou or mil (1 ⁄ 1000 of an inch) inch (25.4 mm) foot (12 inches, 0.3048 m) yard (3 feet, 0.9144 m)
The Academy of Motion Picture Arts & Sciences has postponed the announcement of this year's Oscar nominations for a second time because of the ongoing wildfires in Los Angeles, organizers said on ...
This is a list of units of measurement based on human body parts or the attributes and abilities of humans (anthropometric units). It does not include derived units further unless they are also themselves human-based. These units are thus considered to be human scale and anthropocentric.