Search results
Results from the WOW.Com Content Network
The Argonaute (AGO) gene family encodes six characteristic domains: N- terminal (N), Linker-1 (L1), PAZ, Linker-2 (L2), Mid, and a C-terminal PIWI domain. [ 8 ] The PAZ domain is named for Drosophila Piwi, Arabidopsis Argonaute-1, and Arabidopsis Zwille (also known as pinhead, and later renamed argonaute-10), where the domain was first ...
The structure of several Piwi and Argonaute proteins (Ago) have been solved. Piwi proteins are RNA-binding proteins with 2 or 3 domains: The N-terminal PAZ domain binds the 3'-end of the guide RNA; the middle MID domain binds the 5'-phosphate of RNA; and the C-terminal PIWI domain acts as an RNase H endonuclease that can cleave RNA.
Gathering of the Argonauts, Attic red-figure krater, 460–450 BC (Louvre G 341) The Argonauts (/ ˈ ɑːr ɡ ə n ɔː t / AR-gə-nawt; Ancient Greek: Ἀργοναῦται, romanized: Argonaûtai, lit.
The Argonautidae are a family of pelagic cephalopods that inhabit tropical and temperate oceans of the world. The family encompasses the modern paper nautiluses of the genus Argonauta along with several extinct genera of shelled octopods. Though argonauts are derived from benthic octopuses, they have evolved to depart the sea floor and live ...
Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene. [5] [6] [7] This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain.
The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and argonaute 4. [7]
The argonauts (genus Argonauta, the only extant genus in the family Argonautidae) are a group of pelagic octopuses.They are also called paper nautili, referring to the paper-thin eggcase that females secrete; however, as octopuses, they are only distant relatives of true nautili.
RDE-1 (RNAi-DEfective 1) is a primary Argonaute protein required for RNA-mediated interference (RNAi) in Caenorhabditis elegans.The rde-1 gene locus was first characterized in C. elegans mutants resistant to RNAi, and is a member of a highly conserved Piwi gene family that includes plant, Drosophila, and vertebrate homologs.