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Cefoperazone contains an N-methylthiotetrazole (NMTT or 1-MTT) side chain.As the antibiotic is broken down in the body, it releases free NMTT, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse effect), due to inhibition of aldehyde dehydrogenase.
The Indonesian Food and Drug Authority (Indonesian: Badan Pengawas Obat dan Makanan, lit. 'Food and Drug Supervisory Agency'), Badan POM/BPOM, or Indonesian FDA is a government agency of Indonesia responsible for protecting public health through the control and supervision of prescription and over-the-counter pharmaceutical drugs (medication), vaccines, biopharmaceuticals, dietary supplements ...
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The combination ampicillin/sulbactam (Unasyn) is available in the United States. [3]The combination cefoperazone/sulbactam (Sulperazon) is available in many countries but not in the United States.
PT Industri Jamu dan Farmasi Sido Muncul Tbk, commonly known as Sido Muncul, is an Indonesian herbal medicine and food products company based in Semarang, Indonesia, established in 1940. It produces and markets a variety of consumer products related to herbal medication, such as the jamu Tolak Angin .
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The proportion of the core city's (Jakarta) population to that of the entire metropolitan area also declined significantly. In 2020, the population of Jakarta was only 30.4% of the total population of the Jakarta metropolitan area, continuing the decline from 54.6% in 1990 to 43.2% in 2000 and 35.5% in 2010.