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In statistics, Deming regression, named after W. Edwards Deming, is an errors-in-variables model that tries to find the line of best fit for a two-dimensional data set. It differs from the simple linear regression in that it accounts for errors in observations on both the x - and the y - axis.
It is a generalization of Deming regression and also of orthogonal regression, and can be applied to both linear and non-linear models. The total least squares approximation of the data is generically equivalent to the best, in the Frobenius norm , low-rank approximation of the data matrix.
Procedures for method evaluation and method comparison include ROC curve analysis, [6] Bland–Altman plot, [7] as well as Deming and Passing–Bablok regression. [8] The software also includes reference interval estimation, [9] meta-analysis and sample size calculations.
It may be considered a robust version of reduced major axis regression. The slope estimator b {\displaystyle b} is the median of the absolute values of all pairwise slopes. The original algorithm is rather slow for larger data sets as its computational complexity is O ( n 2 ) {\displaystyle O(n^{2})} .
Linear errors-in-variables models were studied first, probably because linear models were so widely used and they are easier than non-linear ones. Unlike standard least squares regression (OLS), extending errors in variables regression (EiV) from the simple to the multivariable case is not straightforward, unless one treats all variables in the same way i.e. assume equal reliability.
In Deming regression, a type of linear curve fitting, if the dependent and independent variables have equal variance this results in orthogonal regression in which the degree of imperfection of the fit is measured for each data point as the perpendicular distance of the point from the regression line.
Vertical distance: Simple linear regression; Resistance to outliers: Robust simple linear regression; Perpendicular distance: Orthogonal regression (this is not scale-invariant i.e. changing the measurement units leads to a different line.) Weighted geometric distance: Deming regression
Interactive help is available. The program provides methods that are appropriate for matched and independent t-tests, [2] survival analysis, [5] matched [6] and unmatched [7] [8] studies of dichotomous events, the Mantel-Haenszel test, [9] and linear regression. [3]